Combined Qcm and Electrochemical Impedance Measurements for Biosensor Applications
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چکیده
The reproducible degradation of thin polymer films in the presence of an analyte or a reaction product of an analyte can be utilized to produce highly sensitive, disposable biosensors [1, 2]. This type of sensor has been particular useful for the detection of enzyme concentrations. Recent work in this area lead to the development of a sensor for α-chymotrypsin based on the changes in the Surface Plasmon Resonance (SPR) angle produced during the enzyme catalyzed dissolution of poly(ester amide) coatings on SPR substrates. Enzyme concentrations as low as 2×10 M could be detected in less than 20 min [2].
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تاریخ انتشار 2001